hi Kevin. I think you are right about the isolation clips. From what Cascade Audio told me, they primarily isolate but also improve in-room bass response.
Our basement was unfinished, so symmetry in design is a given.
As for acoustic treatments, time will tell. We have some other tricks that should theoretically limit their usel. The multiplicity of opinions on room design is mind boggling.
The room is about 4-6 weeks out. A system thread will follow.
Out of curiosity, have you played with any of the "acoustic resonator" products?